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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b29920afe13c792c0b2c770efa5dbb8a9043ba25d4b6ad9819d1a54246dd4053' 
  AND token = '7+5mC3Z4XE9Q2e6JhjpmQCVvnZb+d1NR0tKrs5Ci0Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}