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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc493f069a014a35ece6314f23a67f5f64cd02beef7d5b142867174f1a727e6a' 
  AND token = 'tb4RvcW8Smsj+992Qf7j1C92gOFEmgvPdw8Q0GgNcq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}