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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e63c4111afcbb6a46905d2ad044dc9b1ef554e219df4372b388b871846f1100' 
  AND token = 'crWmhVwYFjMiemTuw2P5PafokcMqLmH1Wb9dAiTWjTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}