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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aa9b21ab5df28aee60c1b67da152976f0a7c690c917208d05d4663ffd692c42' 
  AND token = '1Q3hyOTOUzzTq3kqBdOK0zuNuspT+T0oeAk+x8jsGEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}