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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a3963231c80b388306878d5a3f7cbe8c1efe9ed8eff49f65e62c2ce7160e9b' 
  AND token = 'dXafifVilkIMB23O8YLQY1ILVwVCHdWnb7TsIgh8ZS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}