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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3647ee5fa77650caa11b9b25d80c3a49d9135c8a178ce6cf0a754d782461d4d5' 
  AND token = 'nyaw4NCKG0lNn9VPlSvywSa7hzV3EnEAre3r/Wowkng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}