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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e64b98e0ff50d291d2bdebdd5fdadb8728d8d1b9022c3d34d768bfcffd33c3a0' 
  AND token = 'nJm1wPI43DcsBdj0mA38juygjWpt7oEP2I71/wvn8/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}