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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '864f11c1c1b08c98a267e687c58062b3aee64d263761fe639be2c30234f206e1' 
  AND token = 'PN2uyh/VaNrwnLpEWRmPOoVM9P8s6YDoUJue9R0TtRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}