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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53aaab46f1a218b6712ee150e45cc544a1f7c8a80bd94e900f0298a22e3d0481' 
  AND token = '1OZIMkGQuvv3DNkvhTqM5YT0BZEro1lAIMgIVVCk0ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}