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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cadff2c8f1326069230046f0e330a8131425c53be3ff86662380f5f9a28cd559' 
  AND token = '4V+IHu4rdZACUyGt1e1yfQQQAg844EvIvEj7UkhgVJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}