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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a49935ad77d6498d46858fe3c9111c62bd9c6876877567678d076dc21438285' 
  AND token = 'p6IFGvSacBpbOdp/rbTLv63DWx0k/jqKM6ipmKFFC84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}