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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39dd6f9eb2f0f9223d067c19c837e1a06e025dd1ff1e20dc0571dbc417f126e2' 
  AND token = '4e61E4YInuPDcyrDPhK1w9cw0GFeypLvMCXMnNEzv8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}