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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b9b790a6a54e5c9fe0e6d235c18da3860a0bbc3bf4bc2f9ac4b06871e14f173' 
  AND token = 'F2pDLwYEnG9Lo4aRTuLyEpvHpPLwXTmY4V2Wg7kfuXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}