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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e37e376cc8a873d473871ad150733f088811c8adab3d16bb0777192cc15c273' 
  AND token = 'VjcvizV9pD6i0D/lY8EjA6oihKs976ThiUZoEEYSh2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}