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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc176592cc2bc75e8e63bb44860d743dddf45cf2d81cabfd642f8eef96e81bb4' 
  AND token = 'rwzskURjegJaejLbcRtSVnNUC9+Y1S6tAe6fR69OfsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}