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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff60863737c275a5623b03dda0fcf39eb7c39b14b2518bcf22659c3b8aadb087' 
  AND token = 'TF/05mtVKxGVollWkAI1g3BW0CaKyVoDQYF2OUdw4Bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}