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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deff5e201d989a87af44d6f0c973f93332b3b51df6a9c01ddb2124d0c94a7f96' 
  AND token = 'B4uj773HZcKMsZQtkKSrk0513F0CidGV1A0TwoxeY5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}