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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c6a23f74937812024185325c7e6a86c343653b89b1be0a37784cb6fe988420c' 
  AND token = 'mVUvouBw/g46yVefMktAS8zryj2AcUBxxw8ukKxFMW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}