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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '439e4d0317abe33da60944e3c86a789fd68ed049ff112c663ca6a9041c8bf4d3' 
  AND token = 'VfKuB+lFqyr6pkBUR3nIhuBnbUApN7bLlB0WS6RW2Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}