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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16cecf06f5b303fd2b48a4facbce9036aa2e13b29b146660dd63e9224e205f2d' 
  AND token = 'SVsBKQk0INLYO4nniLQaLvxQTZWDJR+tDneA65PsC2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}