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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ce072af3db2021ffc5a5aaf1a1ea6fe5aaecf161a268294013b3244f17824f' 
  AND token = 'a0+ux729zOu1/AUCBFZ0dw343TqitOPjO5Tg140b+Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}