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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dad9449e5bbf59c2b35b773e9c3b48326d67e2e7e147c6f097caf6152496c5f' 
  AND token = 'PC9ZPzYYcg1lJ2HzNLSHiXng9c8S19ou2IKiAv8k7kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}