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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143d2e71e4fa5db7bee0a0f419112239304b8d9fee9d06550c232af436a44c0a' 
  AND token = '1b3Wz2FYE6pCiR5P8DX4YcJovkz4nN2v/1E9JO6Cwxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}