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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d2b03d6d65273d4947f29264f6cde393d55eddc46cad5b756fdf2e8c059bc89' 
  AND token = 'vxNVz/7cVs8XS8X342gJQD5CfsYpXUJ3/lyYYgAwd0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}