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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf22ca8ab2898059584d25e9102b29c22e292154691d3d9489a22859558fdc0' 
  AND token = 'Sf9NbvIuuD0jzPeq13lo8PSOmhLWQfpZf9IHRX53fWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}