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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7bd4b1b43d5a8226b1e6bf1d889cad9173cd8a4bae286563a2cfd28b50aa476' 
  AND token = 'LisCGWAmLF8O7ZopFCbXIucQeHGS/ZqB5M1J6xbi1kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}