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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e233ebf2efa255ca3024a47136f8b03ad7e4094dd5dc034c76fc6dec1013bab' 
  AND token = '10fVta9hwkr2azL+/KFYaS/9Qj4giJbmbOxU9Ceo3BU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}