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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e581a453c2623bddbab11c978dfef0daedd1060d2df5caf2eb04164b9359b1e7' 
  AND token = 'z3nc0e695B0QeySEEbpQcTqMHKaFY2FvNromwHEmeis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}