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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d2360c70a61128834efc02e2a9f61e6c4e72fd1f46e5166c94cf643e2c8b839' 
  AND token = 'CzUiW2po4LfdJvGDYnor2egmVCcbg1jT4Zv099QT+D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}