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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ad16118dbda89115a1ee7fe7cb52d05772c285f401e24646ed86deaf4a8832' 
  AND token = 'FUs7aDDLaM1eHtLkwiqeDWlnbsPLxEv56UZNWP+r+0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}