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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c28f5ab36350ae798eb58088a012978232d8c2c1ed932e49d6fd5787dec143c' 
  AND token = 'Q62vKlTzqlCdUJz6vRnO90e6larCDwpWwKi9PHcyH+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}