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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50acbc88395ba6001ca246c2cf386b118df037780fbd94730b629d1a65686e12' 
  AND token = 'edGML0mMZq6Nn6Ojt4kJAFG38M5lqc3L9wu+168kFXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}