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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af6f125722af42129befd8776d5ae2de40f33fa142b50eb9776eb67ac7731088' 
  AND token = 'eKO5TFRxSS996FNV5hfMOqD9YNseSCX4uZXx4BdK7Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}