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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a498667c9f5dca3348d56ff9e6ccd611b74d8d526276e3f0900fe8c6af2f408d' 
  AND token = 'IzguIxJsGrgTIbgj1fo6aU4ZtZANHCMogE+ec0fE/B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}