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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e411d1dd0967884f34f7e7b1453f1b5c8fc33071a78733355d25fbea66b74c4c' 
  AND token = 'mkBXuoDMrRJXl4QZkd4K3sny1AfmItZ70e28pYpyfX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}