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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c3ac432e2b11a53fe081d712fe8160090ba9d32cb77f2e9ed3383e70f26d580' 
  AND token = 'iVY3tKw8hJNK1nTUAULZG1euaEcjARDtjVN+0YsA2mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}