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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7faf56f7bad3c5406e8a51bb61e3ef3f5521722cecf381fcbfbe01061622b098' 
  AND token = 'TQ+ok1NcZDh9sJc9B/2K1jXlaA+phJ1qPVF50HiS93k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}