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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420eaba059cdaebaf8f453d7104bf79469a31b684f36cedde632355d7a770328' 
  AND token = 'wFIE7ium3V15cM4NXlbGAFs0jJYPAkLAxVS+Rgie2AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}