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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '490b867b46864a6e310f5bb283f4e64a4aa8d3af656ee355bcf47eb38740f8aa' 
  AND token = '3EMwiwNca8mCzvrdM9sgtvYwRwlbxLm+OKka2ArC0Co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}