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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6566d9cc422a7d777159c770e4b80d3b75c63b47be0d9f606f8a4262e600fb0b' 
  AND token = 'HA0ofHgn0xxK6Ik2BDEAxM/5nGC/2YK7GHKRPsbugWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}