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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a641eecc28bdd4614d4e2aa553cf506665de13515729228933d4f6c7fcd85a6' 
  AND token = '0GLx9MXs0n35YaWl2+8xuzyCqY0EysH8QaoRshL6lCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}