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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '299366ff9a3e8c7dc043b765f4b4ba171f35e21ed5ea5331063f6fdd5ffe619e' 
  AND token = 'VFxaJl9adblpudb2pVBKtNNZQOPPXWsS7LQhZfznAZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}