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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a6e7dcf50ac486b9b6db55f93da793f8381b08d1c65448b121cac8523cf9188' 
  AND token = 'E/genaHEJCAPRgo/Z/KAMx816sPr0JhibK5i4Aps0hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}