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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed961d32baad7f22ebdda97fce2df0a9847c074aa24220004e35cc87f893cb2' 
  AND token = 'RFc10GGp7ORQWduqobttSQGy1QN3qHtrv4G69WJsQUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}