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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b2ed5c61a154eb4fe530b9d084259aa9918f7c230454f4770268c6b25de0425' 
  AND token = 'nFSys+g9uRCJNgwQBbhPEof13LMwOp70Ia7U7TN44YQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}