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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec852d4ede81e74011b735887139dd2a7f0a79f178b9ba50ae1537169b294a4d' 
  AND token = 'nOD2ZVyIdLatWF5/VZi3/CMyESAsLeKoS6AHFFjS1vA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}