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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a905b91166ad229caad53309ce039d7c592af30d7c2f961760cbb1e6a358d4' 
  AND token = 'kF9Ditqevee3WXB2U4oqkpIaqC/NZ+8tv4Ko76SxsNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}