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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c5872ca792f69423cd003f1b57bb867459d300610ea814437c688df2a7f404' 
  AND token = 'x5qhwPkDS7AqQWtZE0idwMHmw0H8hBejPssAkxhWyWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}