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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f7890ae6bc906a7f300a52d6a71787a4352ffe776b1d104e0087746e4d0b4fa' 
  AND token = 'fVZpEaHJWC0EyWou7tv5xVJ8RsfBerkm2qOL9b4aGXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}