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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e42de9a518cbcc5f65e7c2aa408cdb200fb2d87c694346bf62c0bc77143a2e3' 
  AND token = 'wm8eVeYP8EeLTc8MhmSLBz/MJSKJ/gLft/965ZI3nQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}